Perusioのdrupal-with-nginxリポジトリを見てみましたが、どれほど広大なのかは印象的ですが、現時点では少し高度すぎるかもしれません。さらに、Symfony2ベースのサイトがサーバー上に存在し、構成を完全に理解するまで、大幅な変更を開始しません。
それで、私はブログでこれを見つけて、それが仕事をするかもしれないと思いました。nginx経由でdrupal 7を提供する際によくある落とし穴はありますか?また、同じDrupalインストールで複数のサイトに電力を供給する場合、構成は異なりますか?
server {
    server_name example.org;
    root /home/me/sites/example.org;
    index index.html index.htm index.php;
    access_log /var/log/nginx/example.org.access.log;
    error_log /var/log/nginx/example.org.error.log;
    location = /favicon.ico {
            log_not_found off;
            access_log off;
    }
    location = /robots.txt {
            allow all;
            log_not_found off;
            access_log off;
    }
    # For drush
    location = /backup {
            deny all;
    }
    # Prevent user from accessing settings.php directly
    location ~ ^/sites/[^/]+/settings.php$ {
            deny all;
    }
    ## Replicate the Apache <FilesMatch> directive of Drupal standard
    ## .htaccess. Disable access to any code files. Return a 404 to curtail
    ## information disclosure. Hide also the text files.
    location ~* ^(?:.+\.(?:htaccess|make|txt|log|engine|inc|info|install|module|profile|po|sh|.*sql|theme|tpl(?:\.php)?|xtmpl)|code-style\.pl|/Entries.*|/Repository|/Root|/Tag|/Template)$ {
            return 404;
    }
    location ~ \..*/.*\.php$ {
            return 403;
    }
    location / {
            # This is cool because no php is touched for static content
            try_files $uri @rewrite;
    }
    location @rewrite {
            # Some modules enforce no slash (/) at the end of the URL
            # Else this rewrite block wouldn't be needed (GlobalRedirect)
            #rewrite ^/(.*)$ /index.php?q=$1&$args;
            rewrite ^ /index.php last;
    }
    # Use an SSH tunnel to access those pages. They shouldn't be visible to
    # external peeping eyes.
    location = /install.php {
            allow 127.0.0.1;
            deny all;
    }
    location = /update.php {
            allow 127.0.0.1;
            deny all;
    }
    location ~ \.php$ {
            fastcgi_split_path_info ^(.+\.php)(/.+)$;
            #NOTE: You should have "cgi.fix_pathinfo = 0;" in php.ini
            include fastcgi_params;
            fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name;
            fastcgi_intercept_errors on;
            fastcgi_pass unix:/var/run/php5-cgi/php5.sock;
    }
    ## Drupal 7 generated image handling, i.e., imagecache in core. See:
    ## https://drupal.org/node/371374
    location ~* /sites/.*/files/styles/ {
            access_log off;
            expires 30d;
            try_files $uri @rewrite;
    }
    # Fighting with ImageCache? This little gem is amazing.
    location ~ ^/sites/.*/files/imagecache/ {
            try_files $uri @rewrite;
    }
    location ~* \.(js|css|png|jpg|jpeg|gif|ico)$ {
            expires max;
            log_not_found off;
    }
}